Browsing Department of Medical Sciences by Author "ECHO Trial Team"

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Rationale and design of a multi-center, open-label, randomised clinical trial comparing HIV incidence and contraceptive benefits in women using three commonly-used contraceptive methods (the ECHO study)

Hofmeyr, G. Justus; Morrison, Charles S.; Baeten, Jared M.; Chipato, Tsungai; Donnell, Deborah; Gichangi, Peter; Mugo, Nelly; Nanda, Kavita; Rees, Helen; Steyn, Petrus; Taylor, Douglas; ECHO Trial Team (Gates Open Research, 2018-03-13)

Background: In vitro, animal, biological and observational clinical studies suggest that some hormonal methods, particularly depot medroxyprogesterone acetate – DMPA, may increase women’s risk of HIV acquisition. DMPA is ...